DOPAMINE D1- AND D2-LIKE RECEPTORS OPPOSITELY REGULATE LIFESPAN VIA A DIETARY RESTRICTION MECHANISM IN CAENORHABDITIS ELEGANS

Dopamine D1- and D2-like receptors oppositely regulate lifespan via a dietary restriction mechanism in Caenorhabditis elegans

Abstract Background Despite recent progress in understanding the molecular mechanisms regulating aging and lifespan, and the pathways involved being conserved in different species, a full plate understanding of the aging process has not been reached.In particular, increasing evidence suggests an active role for the nervous system in lifespan regula

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